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REVIEW ARTICLE
Year : 2018  |  Volume : 4  |  Issue : 1  |  Page : 1-5

Primary failure of eruption, A review


Department of Pedodontics and Preventive Dentistry, D. Y. Patil Deemed to be University, School of Dentistry, Navi Mumbai, Maharashtra, India

Correspondence Address:
Dr. Uma B Dixit
Department of Pedodontics and Preventive Dentistry, D. Y. Patil Deemed to be University, School of Dentistry, Nerul, Navi Mumbai, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijohr.ijohr_11_18

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Primary failure of tooth eruption (PFE) is defined as a non-syndromic condition in which non-ankylosed teeth fail to erupt fully or partially due to malfunction of the eruption mechanism. Although the eruption path is clear without any mechanical obstruction like cyst or supernumerary tooth, affected teeth fail to erupt. Patients diagnosed with PFE have revealed mutation in the gene encoding the G protein of parathyroid hormone 1 receptor (PTH1R). The condition is characterized by progressive posterior open bite due to involvement of all the teeth distal to the first affected tooth. These teeth fail to respond to orthodontic forces and attempts to correct open bite orthodontically cause the affected teeth to ankylose, thus worsening the open bite. Diagnosis of PFE is critical as management differs from the infra-occluded teeth due to mechanical obstruction or systemic etiology. This review attempts to discuss etiology, clinical features, diagnosis and management of the teeth affected with primary failure of tooth eruption.


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